Publications

Google scholar list

Machine Learning

Partial label learning for automated classification of single cell transcriptomic profiles
Malek Senoussi, Thierry Artieres*, Paul Villoutreix* – PLoS Computational Biology

Hierarchical classification for weakly supervised transcriptomics data
Malek Senoussi, Thierry Artieres, Paul Villoutreix – CAp, 2022

Cross-View Kernel Transfer
Riikka Huusari, Cécile Capponi, Paul Villoutreix, Hachem Kadri – Pattern Recognition, 2022

What can machine learning do for developmental biology
Paul Villoutreix, invited paper, Development, 2021

Towards a general framework for spatio-temporal transcriptomics
Julie Pinol, Thierry Artières, Paul Villoutreix, NeurIPS LMRL workshop, 2020

Synthesizing developmental trajectories
Paul Villoutreix*, Joakim Andén*, Bomyi LimHang Lu, Yannis Kevrekidis, Amit Singer, Stanislav Y. Shvartsman – PLoS Comput Biol 13(9): e1005742, 2017.

Biologically informed modeling

Random walk informed heterogeneity detection reveals how the lymph node conduit network influences T cells collective exploration behavior
Solène Song, Malek Senoussi, Paul Escande, Paul Villoutreix – PLoS Computational Biology 2023, in press

Entropic effects in cell lineage tree packings
Jasmin Imran Alsous*, Paul Villoutreix*, Norbert Stoop*, Stanislav Y. Shvartsman, Jörn Dunkel – Nature Physics, 14(10), 1016-1021, 2018

Collective Growth in a Simple Cell Network
Jasmin Imran Alsous, Paul Villoutreix, Alexander M. Berezhkovskii, Stanislav Y. Shvartsman – Current Biology 27(17), 2670–2676, 2017.

Single cell morphometrics

Single-cell morphometrics reveals T-box dependent patterns of epithelial tension in the Second Heart field 
Submitted

Application of 3D MAPs pipeline identifies the morphological sequence chondrocytes undergo and the regulatory role of GDF5 in this process
Sarah Rubin, Ankit Agrawal, Johannes Stegmaier, Jonathan Svorai, Yoseph Addadi, Paul Villoutreix*, Tomer Stern*, Elazar Zelzer* – Nature Communications, 2021

Video explaining the main findings : http://vimeo.com/463129275

An integrated modelling framework from cells to organism based on a cohort of digital embryos
Paul Villoutreix*, Julien Delile*, Barbara Rizzi*, Louise Duloquin*, Thierry Savy, Paul Bourgine, René Doursat, Nadine Peyriéras, Scientific Reports, 6:37438, 2016.
Code and Datasets or github repository

Book Chapter

Vers une modélisation multi-échelle de la variabilité biologique?
Paul Villoutreix, Chap. 19 in Modéliser & Simuler. Epistémologies et pratiques de la modélisation et de la simulation. Tome 2, Franck Varenne, Marc Silberstein, Philippe Huneman et Sebastien Dutreuil, Eds. pp. 643 – 664, Editions matériologiques, Novembre 2014.

Ph.D Thesis

Randomness and variability in animal embryogenesis, a multi-scale approach
Paul Villoutreix, PhD Dissertation – Université René Descartes – Paris V, 2015

Others

Piece of news on the Embryo Project Encyclopedia.

Showcase on the Information is Beautiful Award website.

Blog post describing The Embryo Digital Atlas’ journey to the Global Sprint.

Interview on Mozilla Science Lab blog – The Embryo Digital Atlas.

Blog post discussing our work on data-driven visualizations of developing embryos and its relationships to art. This is a supporting webpage for Mozilla Science Lab  community call on art and science.