{"id":28,"date":"2020-08-24T14:18:08","date_gmt":"2020-08-24T14:18:08","guid":{"rendered":"https:\/\/bioml.lis-lab.fr\/?page_id=28"},"modified":"2025-03-06T07:55:47","modified_gmt":"2025-03-06T07:55:47","slug":"publications","status":"publish","type":"page","link":"https:\/\/bioml.lis-lab.fr\/index.php\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n<p><a href=\"https:\/\/scholar.google.fr\/citations?hl=en&amp;user=uaK6xaYAAAAJ&amp;view_op=list_works&amp;sortby=pubdate\" data-type=\"URL\" data-id=\"https:\/\/scholar.google.fr\/citations?hl=en&amp;user=uaK6xaYAAAAJ&amp;view_op=list_works&amp;sortby=pubdate\">Google scholar list<\/a><\/p>\n\n\n\n<p><strong>Machine Learning<\/strong><\/p>\n\n\n\n<p><em>MODIS: Multi-omics data integration for small and unpaired datasets<\/em><br>Daniel Lepe-Soltero, Thierry Arti\u00e8res, Ana\u00efs Baudot, Paul Villoutreix, LMRL workshop, ICLR 2025<\/p>\n\n\n\n<p><em><a href=\"https:\/\/arxiv.org\/abs\/2409.05937\">Hierarchical novel class discovery for single-cell transcriptomic profiles<\/a><br><\/em>Malek Senoussi, Thierry Arti\u00e8res, Paul Villoutreix &#8211;&nbsp;arXiv, 2024<\/p>\n\n\n\n<p><em><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.03.22.586210v1.full.pdf\">MOTL: enhancing multi-omics matrix factorization with transfer learning&nbsp;<\/a><br><\/em>David Hirst, Morgane T\u00e9r\u00e9zol, Laura Cantini, Paul Villoutreix, Matthieu Vignes, Ana\u00efs Baudot &#8211; in review<\/p>\n\n\n\n<p><em><span style=\"text-decoration: underline;\">Partial label learning for automated classification of single cell transcriptomic profiles<\/span><\/em><br>Malek Senoussi, Thierry Artieres*, Paul Villoutreix* &#8211; PLoS Computational Biology<\/p>\n\n\n\n<p><em><span style=\"text-decoration: underline;\">Hierarchical classification for weakly supervised transcriptomics data<\/span><\/em><br>Malek Senoussi, Thierry Artieres, Paul Villoutreix &#8211; CAp, 2022<\/p>\n\n\n\n<p><em><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0031320322002400\">Cross-View Kernel Transfer<\/a><\/em><br>Riikka Huusari, C\u00e9cile Capponi, Paul Villoutreix, Hachem Kadri \u2013 Pattern Recognition, 2022<\/p>\n\n\n\n<p><em><a href=\"https:\/\/dev.biologists.org\/content\/148\/1\/dev188474\">What can machine learning do for developmental biology<br><\/a><\/em>Paul Villoutreix, invited paper,<em> Development,<\/em>&nbsp;2021<\/p>\n\n\n\n<p><em><a href=\"https:\/\/hal.archives-ouvertes.fr\/hal-03154958\/document\" data-type=\"URL\" data-id=\"https:\/\/hal.archives-ouvertes.fr\/hal-03154958\/document\">Towards a general framework for spatio-temporal transcriptomics<\/a><\/em><br>Julie Pinol, Thierry Arti\u00e8res, Paul Villoutreix,&nbsp;<em>NeurIPS LMRL workshop, <\/em>2020<\/p>\n\n\n\n<p><em><a href=\"http:\/\/journals.plos.org\/ploscompbiol\/article?id=10.1371\/journal.pcbi.1005742\">Synthesizing developmental trajectories<\/a><br><\/em>Paul Villoutreix<em>*,&nbsp;<\/em>Joakim And\u00e9n<em>*,<\/em>&nbsp;Bomyi Lim<em>,&nbsp;<\/em>Hang Lu, Yannis Kevrekidis, Amit Singer, Stanislav Y. Shvartsman &#8211; PLoS Comput Biol 13(9): e1005742, 2017.<\/p>\n\n\n\n<p><strong>Single cell morphometrics<\/strong><\/p>\n\n\n\n<p><em><a href=\"https:\/\/rdcu.be\/dY48Q\" data-type=\"link\" data-id=\"https:\/\/rdcu.be\/dY48Q\">Single-cell morphometrics reveals T-box gene-dependent patterns of epithelial tension in the Second Heart field<\/a><\/em><br><span style=\"white-space: normal; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-size: medium;\"><\/span>Clara Guijarro+, Sol\u00e8ne Song+, Benoit Aigouy, Raphael Clement, Paul Villoutreix*, Robert G. Kelly* &#8211; in press, Nature Communications, 2024<\/p>\n\n\n\n<p><a href=\"https:\/\/elifesciences.org\/articles\/95289\"><em>Limited column formation in the embryonic growth plate implies divergent growth mechanisms during pre- and postnatal bone development<\/em><\/a><br>Sarah Rubin, Ankit Agrawal, Anne Seewald, Meng-Jia Lian, Livia Gottdenker, Paul Villoutreix, Adrian Baule, Tomer Stern, Elazar Zelzer &#8211; eLife, 2024<\/p>\n\n\n\n<p><em><a href=\"https:\/\/www.nature.com\/articles\/s41467-021-25714-0\">Application of 3D MAPs pipeline identifies the morphological sequence chondrocytes undergo and the regulatory role of GDF5 in this process<\/a><\/em><br>Sarah Rubin, Ankit Agrawal, Johannes Stegmaier, Jonathan Svorai, Yoseph Addadi, Paul Villoutreix*, Tomer Stern*, Elazar Zelzer* &#8211;&nbsp;<em>Nature Communications<\/em>, 2021<\/p>\n\n\n\n<p>Video explaining the main findings :&nbsp;<a href=\"http:\/\/vimeo.com\/463129275\">http:\/\/vimeo.com\/463129275<\/a><\/p>\n\n\n\n<p><em><a href=\"http:\/\/www.nature.com\/articles\/srep37438\">An integrated modelling framework from cells to organism based on a cohort of digital embryos<\/a><br><\/em>Paul Villoutreix*, Julien Delile*, Barbara Rizzi*, Louise Duloquin*, Thierry Savy, Paul Bourgine, Ren\u00e9 Doursat, Nadine Peyri\u00e9ras, Scientific Reports, 6:37438, 2016.<br><a href=\"http:\/\/bioemergences.eu\/bioemergences\/pubs\/seaurchin\">Code and Datasets<\/a>&nbsp;or&nbsp;<a href=\"https:\/\/github.com\/paulvill\/Sea-Urchin\">github repository<\/a><\/p>\n\n\n\n<p><strong>Single-cell transcriptomics<\/strong><\/p>\n\n\n\n<p><em><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.10.02.616294v1\">Spatial reconstruction of single-cell enhancer activity in a multicellular<\/a><\/em><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.10.02.616294v1\">&nbsp;<em>organism<\/em><\/a><br>Baptiste Alberti, S\u00e9verine Vincent, Isabelle St\u00e9vant, Damien Lajoignie, H\u00e9l\u00e8ne Tarayre, Paul Villoutreix, Yad Ghalvi-Helm &#8211; bioRxiv 2024<\/p>\n\n\n\n<p><em><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0012160624002410\">Left\/right asymmetrically expressed ephrin and Flamingo proteins regulate lateralized axon growth in C. elegans<\/a>&nbsp;&nbsp;<\/em><br>Khulganaa Buyannemekh, Paul Villoutreix, Vincent Bertrand &#8211; Developmental Biology, 2024<\/p>\n\n\n\n<p><strong>Biologically informed modeling<\/strong><\/p>\n\n\n\n<p><em><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.07.25.605053v1.full.pdf\">Assessing the relative contributions of mosaic and regulatory developmental modes from single-cell trajectories<\/a><\/em><br>Sol\u00e8ne Song, Paul Villoutreix &#8211; bioRxiv, 2024<\/p>\n\n\n\n<p><em><a href=\"https:\/\/journals.plos.org\/ploscompbiol\/article?id=10.1371\/journal.pcbi.1011168\" data-type=\"URL\" data-id=\"https:\/\/journals.plos.org\/ploscompbiol\/article?id=10.1371\/journal.pcbi.1011168\">Random walk informed heterogeneity detection reveals how the lymph node conduit network influences T cells collective exploration behavior<\/a><br><\/em>Sol\u00e8ne Song, Malek Senoussi, Paul Escande, Paul Villoutreix &#8211; PLoS Computational Biology 2023, in press<\/p>\n\n\n\n<p><em><a href=\"https:\/\/www.nature.com\/articles\/s41567-018-0202-0\">Entropic effects in cell lineage tree packings<\/a><br><\/em>Jasmin Imran Alsous*, Paul Villoutreix*, Norbert Stoop*, Stanislav Y. Shvartsman, J\u00f6rn Dunkel&nbsp;&#8211; Nature Physics, 14(10), 1016-1021, 2018<\/p>\n\n\n\n<p><em><a href=\"http:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(17)30897-7\">Collective Growth in a Simple Cell Network<\/a><br><\/em>Jasmin Imran Alsous, Paul Villoutreix, Alexander M. Berezhkovskii, Stanislav Y. Shvartsman &#8211; Current Biology 27(17), 2670\u20132676, 2017.<\/p>\n\n\n\n<p><strong>Book Chapter<\/strong><\/p>\n\n\n\n<p><em><a href=\"http:\/\/www.cairn.info\/article.php?ID_ARTICLE=EDMAT_VAREN_2014_01_0643\">Vers une mod\u00e9lisation multi-\u00e9chelle de la variabilit\u00e9 biologique?<\/a><\/em><br>Paul Villoutreix, Chap. 19 in&nbsp;<a href=\"http:\/\/materiologiques.com\/modelisations-simulations-systemes-complexes-2425-5661\/187-modeliser-simuler-epistemologies-et-pratiques-de-la-modelisation-et-de-la-simulation-tome-2-9782919694723.html\" target=\"_blank\" rel=\"noreferrer noopener\">Mod\u00e9liser &amp; Simuler. Epist\u00e9mologies et pratiques de la mod\u00e9lisation et de la simulation. Tome 2<\/a>, Franck Varenne, Marc Silberstein, Philippe Huneman et Sebastien Dutreuil, Eds. pp. 643 &#8211; 664, Editions mat\u00e9riologiques, Novembre 2014.<\/p>\n\n\n\n<p><strong>Ph.D Thesis<\/strong><\/p>\n\n\n\n<p><em><a href=\"https:\/\/tel.archives-ouvertes.fr\/tel-01410227\/document\">Randomness and variability in animal embryogenesis, a multi-scale approach<\/a><br><\/em>Paul Villoutreix, PhD Dissertation &#8211; Universit\u00e9 Ren\u00e9 Descartes &#8211; Paris V, 2015<\/p>\n\n\n\n<p><strong>Others<\/strong><\/p>\n\n\n\n<p><a href=\"http:\/\/embryo.asu.edu\/news\/new-digital-tool-visualize-embryogenesis\">Piece of news<\/a>&nbsp;on the Embryo Project Encyclopedia.<\/p>\n\n\n\n<p>Showcase on the&nbsp;<a href=\"https:\/\/www.informationisbeautifulawards.com\/showcase\/2238-the-embryo-digital-atlas\">Information is Beautiful Award website<\/a>.<\/p>\n\n\n\n<p><a href=\"https:\/\/paulcinq.wordpress.com\/the-embryo-digital-atlas-journey-to-mozillas-global-sprint-2017\/\">Blog post<\/a>&nbsp;describing The Embryo Digital Atlas&#8217; journey to the&nbsp;<a href=\"https:\/\/mozilla.github.io\/global-sprint\/\">Global Sprint<\/a>.<\/p>\n\n\n\n<p><a href=\"https:\/\/science.mozilla.org\/blog\/the-embryo-digital-atlas-mozsprint-2017-interview-series\">Interview<\/a>&nbsp;on Mozilla Science Lab blog &#8211;&nbsp;<a href=\"http:\/\/embryodigitalatlas.org\/\">The Embryo Digital Atlas<\/a>.<\/p>\n\n\n\n<p><a href=\"https:\/\/paulcinq.wordpress.com\/about\/data-driven-visualizations-of-embryogenesis\/\">Blog post<\/a>&nbsp;discussing our work on data-driven visualizations of developing embryos and its relationships to art. This is a supporting webpage for&nbsp;<a href=\"https:\/\/science.mozilla.org\/\">Mozilla Science Lab<\/a>&nbsp;&nbsp;<a href=\"https:\/\/science.mozilla.org\/programs\/events\/community-call-feb-16-11-et\">community call<\/a>&nbsp;on art and science.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Google scholar list Machine Learning MODIS: Multi-omics data integration for small and unpaired datasetsDaniel Lepe-Soltero, Thierry Arti\u00e8res, Ana\u00efs Baudot, Paul Villoutreix, LMRL workshop, ICLR 2025 Hierarchical novel class discovery for single-cell transcriptomic profilesMalek Senoussi, Thierry Arti\u00e8res, Paul Villoutreix &#8211;&nbsp;arXiv, 2024 MOTL: enhancing multi-omics matrix factorization with transfer learning&nbsp;David Hirst, Morgane T\u00e9r\u00e9zol, Laura Cantini, Paul Villoutreix, &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/bioml.lis-lab.fr\/index.php\/publications\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Publications&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-28","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/bioml.lis-lab.fr\/index.php\/wp-json\/wp\/v2\/pages\/28","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioml.lis-lab.fr\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioml.lis-lab.fr\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioml.lis-lab.fr\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/bioml.lis-lab.fr\/index.php\/wp-json\/wp\/v2\/comments?post=28"}],"version-history":[{"count":25,"href":"https:\/\/bioml.lis-lab.fr\/index.php\/wp-json\/wp\/v2\/pages\/28\/revisions"}],"predecessor-version":[{"id":290,"href":"https:\/\/bioml.lis-lab.fr\/index.php\/wp-json\/wp\/v2\/pages\/28\/revisions\/290"}],"wp:attachment":[{"href":"https:\/\/bioml.lis-lab.fr\/index.php\/wp-json\/wp\/v2\/media?parent=28"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}